About Regis J. O’Keefe, MD, PhD, FAOA
Regis J. O’Keefe, MD, PhD, FAOA is the Fred C. Reynolds Professor and Chair, Department of Orthopaedic Surgery at Washington University School of Medicine in St. Louis, Missouri. Dr. O’Keefe earned his BA in philosophy and religious studies and graduated magna cum laude at Yale University in New Haven, Connecticut. After earning his medical degree from Harvard Medical School in Boston, Massachusetts, he completed a Ph.D. in biochemistry and biophysics from the University of Rochester School of Medicine and Dentistry. Dr. O’Keefe served his internship in surgery at New England Deaconess Hospital in Boston, his residency in orthopaedics at the University of Rochester Medical Center and completed an oncology fellowship at the Massachusetts General Hospital. In 1993, he joined the faculty at the University of Rochester. Dr. O’Keefe previously served as the Marjorie Strong Wehle Professor and Chair, Department of Orthopaedics and Rehabilitation and Associate Dean of Clinical Affairs at the University of Rochester School of Medicine and Dentistry.
Dr. O’Keefe has worked diligently in his career to promote and advance the basic understanding of musculoskeletal diseases and to translate these discoveries into therapies designed to improve the care of orthopaedic patients. He is an author of more than 260 articles, 16 book chapters and reviews concerning bone repair and development, cancer, inflammatory diseases of bone, genetics, and related topics. Dr. O’Keefe has more than 25 years of continuous funding from the NIH. He is a past recipient of the Kappa Delta Award. In 2014, Dr. O’Keefe received the ORS/OREF Distinguished Investigator Award for lifetime contributions to the field of musculoskeletal research.
Dr. O’Keefe has held a number of leadership positions in national organizations. Dr. O’Keefe is a past-President of the Orthopaedic Research Society (ORS). He also served the ORS as Treasurer and as a member of the Program Committee. Dr. O’Keefe is currently a member of the Board of Directors of the American Board of Orthopaedic Surgery (ABOS). He has served as the Secretary and member of the Board of Directors of the Orthopaedic Research and Education Foundation. Dr. O’Keefe is the past-President of the United States Bone and Joint Decade, an international coalition of healthcare organizations aimed at decreasing the incidence of bone and joint disorders. He is a member of the American Association of Physicians (AAP).
Dr. O’Keefe has a long term commitment to the peer review process and to the mentoring of the next generation of academic leaders. Dr. O’Keefe has served as Chair of the Skeletal Biology and Skeletal Regeneration Study Section for the National Institutes of Health’s Center for Scientific Review and he has served on the Advisory Council of the National Institutes of Health (NIH) National Arthritis and Musculoskeletal and Skin Diseases (NIAMS) as well as the National Institutes of Health Council of Councils (COC) Advisory Council that reviews trans-NIH initiatives. Dr. O’Keefe has served as the Chair of the American Academy of Orthopaedic Surgeons’ Clinician Scientist Committee where he initiated the AAOS/ORS/OREF Clinician Scientist Development Program. He also has directed the Orthopaedic Research and Education Foundation’s Grant Writing Workshop, a program that mentors young scientists in the critical skill of grant writing.
Dr. O’Keefe has served The American Orthopaedic Association in a variety of roles. Dr. O’Keefe is a former ABC Traveling Fellow and he served as chair of the Critical Issues Committee prior to joining the AOA presidential line. Dr. O’Keefe’s career focus is aligned with the AOA mission to engage the orthopaedic community to develop leaders, strategies and resources to guide the future of musculoskeletal care.
Carol and Regis O’Keefe have been married for 33 years and enjoy spending time with their 4 children. They currently live with their two dogs in the Central West End area of St. Louis in a historic home that they extensively renovated.